Artificial Intelligence

Note

• Autoregressive Approach:
  • AlphaFold 2, Nature, 2021
  • RoseTTAFold2, bioRxiv, 2023
• Diffusion Approach:
  • RFDiffusion, Nature, 2023
  • RoseTTAFold All-Atom, Science, 2024
  • AlphaFold 3 (All-Atom), Nature, 2024
• Foundation Models:
  • 2024 Nature - A pathology foundation model for cancer diagnosis and prognosis prediction
  • [RNA] 2024 Nature Machine Intelligence - Multi-purpose RNA language modelling with motif-aware pretraining and type-guided fine-tuning
  • [scRNA-seq] 2024 Nature Methods - Large-scale foundation model on single-cell transcriptomics

4 steps of Machine Learning