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Single-Cell-seq Tech.

0. Novel RNA-seq

  • ✅ 2024 Nature Biotech. - RIP-PEN-seq identifies a class of kink-turn RNAs as splicing regulators
  • ✅ 2021 NBT - Quantitative mapping of the cellular small RNA landscape with AQRNA-seq

I. sc-Total_RNA

  • 2024 Nature Communications - Single-cell total-RNA profiling unveils regulatory hubs of transcription factors
  • ✅ 2022 Nature Biotech. - High-throughput total RNA sequencing in single cells using VASA-seq
  • 2022 Nature Biotech. Spatial mapping of the total transcriptome by in situ polyadenylation
  • [mbRNA split-pool] 2020 Science - Microbial single-cell RNA sequencing by split-pool barcoding
  • ✅ [scRNA split-pool] - 2018 Science - SPLiT-seq reveals cell types and lineages in the developing brain and spinal cord

II. scMulti-Omics

  • ✅ 2024 Nature - Single-cell multiplex chromatin and RNA interactions in ageing human brain
  • [Review] 2024 EMM - Advances in single-cell omics and multiomics for high-resolution molecular profiling
  • [Review] 2023 Nature Genetics - Methods and applications for single-cell and spatial multi-omics
  • ✅ 2022 Nature Methods - ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells
  • ✅ [Split-pool RNA+ATAC] 2020 Cell - Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin
  • [Split-pool RNA+ATAC] 2019 Nature Structure Molecular Biology - An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome
  • [scATAC - split-pool] 2019 Nat. Biotechnol. - Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility.
  • [review] 2017 Trend in Genetics - Single-Cell Multiomics: Multiple Measurements from Single Cells *

III. scRNA-mod

  • ✅ 2023 Nature Biotechnology - Single-cell m6A mapping in vivo using picoMeRIP–seq
  • 2023 Nature Review - The roles and implications of RNA m6A modification in cancer
  • 2023 Nature Commn. - scm6A-seq reveals single-cell landscapes of the dynamic m6A during oocyte maturation and early embryonic development
  • ✅ 2022 Nature Methods - Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution
  • 2022 Nature Biotech. - Absolute quantification of single-base m6A methylation in the mammalian transcriptome using GLORI
  • 2022 Mol. Cell - scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells.
  • [RNA mod Review] - 2022 Experimental & Molecular Medicine - Detection technologies for RNA modifications
  • 2019 PNAS - Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution

IV. scRibo-seq

  • ✅ 2021 Nature - Single-cell Ribo-seq reveals cell cycle-dependent translational pausing
  • 2022 NAR - Identifying ribosome heterogeneity using ribosome profiling